Mini review: Persister cell control strategies

Bacterial persisters are growth-arrested cells with low metabolic activities, but have no genetic mutations compared to their parental cells. The dormant nature of persister cells enables them to tolerate high doses of conventional antibiotics and restart growth after the antibiotic is withdrawn, posing an important challenge to infection control. To promote more research in this important area, we present a concise review of current persister control strategies and discuss future opportunities.

Authors

Institutions

Publication Details

Journal
Frontiers in Pharmacology
Published
2025-10-15
DOI
https://doi.org/10.3389/fphar.2025.1706115
Citations
2
Primary Topic
RNA Interference and Gene Delivery
Type
article
Field-Weighted Citation Impact
1.61

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Mini review: Persister cell control strategies

Dacheng Ren, Mohamad Javad Hashemi, Yousr Dhaouadi Khattab
2 citations
Frontiers in Pharmacology
RNA Interference and Gene Delivery
1.61
article

Mini review: Persister cell control strategies

Dacheng Ren, Mohamad Javad Hashemi, Yousr Dhaouadi Khattab
article en
2 citations

Abstract

Bacterial persisters are growth-arrested cells with low metabolic activities, but have no genetic mutations compared to their parental cells. The dormant nature of persister cells enables them to tolerate high doses of conventional antibiotics and restart growth after the antibiotic is withdrawn, posing an important challenge to infection control. To promote more research in this important area, we present a concise review of current persister control strategies and discuss future opportunities.

Frontiers in PharmacologyVol. 16
Knoxville College (US), Syracuse University (US), University of Tennessee at Knoxville (US)
National Institutes of Health
Openalex Percentile: Top 14%
RNA Interference and Gene Delivery
1.61
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.