Elucidating the outpatient burden of lower respiratory tract infections due to RSV and other viruses in children under 2 years of age: Clinical presentation, medical treatment, and family impact (Germany, 11/2022-10/2024)

Outpatient-treated LRTI in infants were usually mild/moderate but resolved slowly, with substantial family impact. RSV, rhinovirus, and hMPV predominated. Wheezing was reported in one-third after 12 months and was associated with recurrent LRTI. The present results provide a basis for assessing the impact of the recently recommended RSV immunization for all infants in Germany on the substantial burden of outpatient-treated LRTI in this particularly vulnerable age group.