Impacts of tacrolimus and glucocorticoids on peripheral blood T and B lymphocyte subsets in myasthenia gravis

Compared with patients receiving glucocorticoid therapy, those treated with tacrolimus exhibited significantly lower levels of peripheral CD3<sup>+</sup>CD4<sup>+</sup> T cells after treatment. These findings provide insight into the differential immunomodulatory effects of these therapies in MG.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-10-15
DOI
https://doi.org/10.3389/fimmu.2025.1667799
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
Field-Weighted Citation Impact
0.00

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article

Impacts of tacrolimus and glucocorticoids on peripheral blood T and B lymphocyte subsets in myasthenia gravis

Huanhuan Song, Xuan Wu, Wei Chen, Guorong Xu
Frontiers in Immunology
Myasthenia Gravis and Thymoma
article

Impacts of tacrolimus and glucocorticoids on peripheral blood T and B lymphocyte subsets in myasthenia gravis

Huanhuan Song, Xuan Wu, Wei Chen, Guorong Xu
article en

Abstract

Compared with patients receiving glucocorticoid therapy, those treated with tacrolimus exhibited significantly lower levels of peripheral CD3<sup>+</sup>CD4<sup>+</sup> T cells after treatment. These findings provide insight into the differential immunomodulatory effects of these therapies in MG.

Frontiers in ImmunologyVol. 16
Fujian Medical University (CN), First Affiliated Hospital of Fujian Medical University (CN)
Natural Science Foundation of Fujian Province
Openalex Percentile: Top 58%
Myasthenia Gravis and Thymoma
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