Antimicrobial susceptibility and molecular characteristics of Mycoplasma pneumoniae isolates from children in Xi'an regions of China

MP strains in Xi'an show high rates of genotypic macrolide resistance and a predominance of the P1-I genotype. The notable discordance between the universal presence of resistance mutations and observed phenotypic resistance underscores the importance of integrating both molecular and culture-based susceptibility testing to guide effective clinical management.

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Publication Details

Journal
Frontiers in Pediatrics
Published
2025-10-15
DOI
https://doi.org/10.3389/fped.2025.1660687
Primary Topic
Pneumonia and Respiratory Infections
Type
article
Field-Weighted Citation Impact
0.00
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article

Antimicrobial susceptibility and molecular characteristics of Mycoplasma pneumoniae isolates from children in Xi'an regions of China

Jianjun Liu, Chao Huang, Jun Yang, Jia Cao et al.
Frontiers in Pediatrics
Pneumonia and Respiratory Infections
article

Antimicrobial susceptibility and molecular characteristics of Mycoplasma pneumoniae isolates from children in Xi'an regions of China

Jianjun Liu, Chao Huang, Jun Yang, Jia Cao, Haiyan Ren, Nan Gao
article en

Abstract

MP strains in Xi'an show high rates of genotypic macrolide resistance and a predominance of the P1-I genotype. The notable discordance between the universal presence of resistance mutations and observed phenotypic resistance underscores the importance of integrating both molecular and culture-based susceptibility testing to guide effective clinical management.

Frontiers in PediatricsVol. 13
Xi'an Chest Hospital (CN)
Openalex Percentile: Top 61%
Pneumonia and Respiratory Infections
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