Case Report: Nystagmus as a core presenting sign in pediatric anti-Ma2 antibody-associated cerebellar ataxia: diagnostic implications from clinical and serological profiling

Nystagmus was first identified in pediatric patients with anti-Ma2 antibody-associated syndrome, expanding clinicians' knowledge of the phenotype in children. Our case demonstrates that IVIG and steroids induced rapid and sustained remission despite presumed cell-mediated immunity cases, with complete symptom resolution within 8 weeks and no recurrence at 1-year follow-up. We also emphasize CBA's superior accessibility and its higher sensitivity and specificity in detecting low-titer antibodies for detecting antibodies in autoimmune encephalitis, particularly in mild or atypical presentations.