Increasing arterial compliance by laser modification of fibro-calcific plaques
This proof-of-concept study demonstrated that modulated diode laser irradiation can modify the mechanical and structural characteristics of fibrocalcific arteries and increase vessel compliance. Additional studies are required in arteries with different levels of calcification and plaque distribution to optimize laser dosimetry for targeted vessel modifications.
Authors
- Yulia M. Alexandrovskaya (ORCID: https://orcid.org/0000-0003-3650-641X)
- Giulio Guagliumi (ORCID: https://orcid.org/0000-0001-6814-2003)
- Driton Vela (ORCID: https://orcid.org/0000-0002-3557-8748)
- J. E. Johnson
- Andreas Glatz (ORCID: https://orcid.org/0000-0002-2007-3851)
- Emil N. Sobol (ORCID: https://orcid.org/0000-0002-6081-8918)
- Freddy Romero (ORCID: https://orcid.org/0000-0002-0389-9010)
- Thomas E. Milner
- V. M. Vinokur (ORCID: https://orcid.org/0000-0002-0977-3515)
- Jennifer King
- S. Rajebahadur
- N. Velluva Rayaroth
Institutions
- Northern Illinois University (US)
- Michael E. DeBakey VA Medical Center (US)
- Baylor College of Medicine (US)
- University of California, Irvine (US)
- Istituto Clinico Sant'Ambrogio (IT)
- Terra Quantum (Switzerland) (CH)
- Beckman Laser Institute and Medical Clinic (US)
- Irvine University (US)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-10-15
- DOI
- https://doi.org/10.3389/fcvm.2025.1652529
- Primary Topic
- Pain Management and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00