Growth factor and hypoxia-inducible factor alpha content in the retina of male Wistar rats in experimental diabetic retinopathy and the effect of cellular protein kinase blockade

The significance of VEGF and HIF-1α upregulation in the pathogenesis of DR and the effectiveness of their correction by pharmacological blockade of cellular protein kinases with sorafenib have been established.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-10-15
DOI
https://doi.org/10.3389/fendo.2025.1643445
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Growth factor and hypoxia-inducible factor alpha content in the retina of male Wistar rats in experimental diabetic retinopathy and the effect of cellular protein kinase blockade

Mihaly Babenko, Kateryna Strubchevska, K.O. Usenko, Marko Kozyk et al.
Frontiers in Endocrinology
Retinal Diseases and Treatments
article

Growth factor and hypoxia-inducible factor alpha content in the retina of male Wistar rats in experimental diabetic retinopathy and the effect of cellular protein kinase blockade

Mihaly Babenko, Kateryna Strubchevska, K.O. Usenko, Marko Kozyk, С. В. Зябліцев, S. О. Rykov, Olena Strubchevska, Oleksandra Kozyk
article en

Abstract

The significance of VEGF and HIF-1α upregulation in the pathogenesis of DR and the effectiveness of their correction by pharmacological blockade of cellular protein kinases with sorafenib have been established.

Frontiers in EndocrinologyVol. 16
Jagiellonian University (PL), Willamette University (US), Kyiv Medical University (UA), Beaumont Hospital, Royal Oak (US), Beaumont Hospital, Troy (US), Szpital Uniwersytecki w Krakowie (PL)
Openalex Percentile: Top 57%
Retinal Diseases and Treatments
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