Differences in growth in prepubertal children with definite growth hormone deficiency, short stature unresponsive to stimulation tests, and idiopathic short stature treated with recombinant human growth hormone: a retrospective study
Despite initial differences, children with SUS responded similarly to rhGH as dGHD patients, while ISS patients had a less favorable response. These findings support the importance of subclassifying short stature conditions to refine diagnostic processes, enhance treatment approaches, and improve growth outcome predictions.
Authors
- Maria Andrea Lanzetta
- Martin Carlsson (ORCID: https://orcid.org/0000-0003-3106-0754)
- Gianluca Tamaro (ORCID: https://orcid.org/0000-0003-1635-9141)
- Gianluca Tornese (ORCID: https://orcid.org/0000-0002-4395-3915)
- Daria La Torre
Institutions
- University of Trieste (IT)
- Pfizer (United States) (US)
- IRCCS Materno Infantile Burlo Garofolo (IT)
- Pfizer (Italy) (IT)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-10-15
- DOI
- https://doi.org/10.3389/fendo.2025.1628072
- Primary Topic
- Growth Hormone and Insulin-like Growth Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Pfizer
- Ministero della Salute