Quantification of Tryptophan and <scp>NAD</scp> <sup>+</sup> Proton Magnetization Exchange With Water Using Downfield <scp> <sup>1</sup> H MRS </scp> in the Human Brain at 7 T
Tryptophan chemical exchange and NAD<sup>+</sup> cross-relaxation with water can be quantified in vivo in human brain at 7 T using downfield spectroscopy.
Authors
- Sophia Swago (ORCID: https://orcid.org/0000-0001-8334-4746)
- Ravi Prakash Reddy Nanga (ORCID: https://orcid.org/0000-0002-3644-5656)
- Ravinder Reddy (ORCID: https://orcid.org/0000-0003-4580-2392)
- Walter R T Witschey (ORCID: https://orcid.org/0000-0003-1669-2120)
- Mark A. Elliott (ORCID: https://orcid.org/0000-0003-2560-8760)
- Neil Wilson (ORCID: https://orcid.org/0009-0002-7766-2929)
Institutions
- University of Pennsylvania (US)
Publication Details
- Journal
- Magnetic Resonance in Medicine
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1002/mrm.70134
- Citations
- 1
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- National Heart, Lung, and Blood Institute