Cryptococcus neoformans phospholipase B1 is critical for cryptococcoma formation in the mouse brain
These results emphasize the need for further investigation into the mechanisms underlying the pathogenicity of <i>Cn</i>. In addition, our findings provide further evidence to validate PLB1 as an important antifungal target.
Authors
- Marta Reguera-Gómez
- Luis R. Martinez (ORCID: https://orcid.org/0000-0001-6372-6501)
- Glauber Ribeiro de Sousa Araújo (ORCID: https://orcid.org/0000-0002-5478-9006)
- Bruno Pontes (ORCID: https://orcid.org/0000-0002-0831-1204)
- Mohamed F. Hamed (ORCID: https://orcid.org/0000-0003-2392-8453)
- Hiu Ham Lee
- Karina Alviña (ORCID: https://orcid.org/0000-0002-8369-0953)
- Susana Frasés (ORCID: https://orcid.org/0000-0001-5875-9886)
- Melissa E. Munzen
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Mansoura University (EG)
- University of Florida (US)
- New York Institute of Technology (US)
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (BR)
- Florida College (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-15
- DOI
- https://doi.org/10.3389/fimmu.2025.1681033
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00