Oncolytic Maraba Virus MG1 Mediates Direct and Natural Killer Cell-Dependent Lysis of Ewing Sarcoma
The ability of MG1 to kill EWS cells directly and stimulate NK cell cytotoxicity against this tumour suggests that MG1 may provide therapeutic benefit for EWS patients where the efficacy of conventional treatments is currently limited.
Authors
- Graham P. Cook (ORCID: https://orcid.org/0000-0003-0223-3652)
- Heather Owston (ORCID: https://orcid.org/0000-0002-9860-9118)
- Javed Khan (ORCID: https://orcid.org/0000-0002-5858-0488)
- Susan A. Burchill (ORCID: https://orcid.org/0000-0002-1034-3723)
- Tyler Barr (ORCID: https://orcid.org/0009-0008-5291-461X)
- Victoria A. Jennings
- Fiona Errington‐Mais (ORCID: https://orcid.org/0000-0003-2155-534X)
- Natasha J. Caplen (ORCID: https://orcid.org/0000-0002-0001-9460)
- Richard Baugh (ORCID: https://orcid.org/0000-0003-4966-6025)
- Dennis McGonagle (ORCID: https://orcid.org/0000-0001-7715-8226)
- Elizabeth A. Roundhill (ORCID: https://orcid.org/0000-0002-0508-3648)
- Peter Vasilios Giannoudis (ORCID: https://orcid.org/0000-0002-5205-7696)
- J C Bell
- Maisa Yamrali
Institutions
- Ottawa Hospital (CA)
- St James's University Hospital (GB)
- National Cancer Institute (US)
- Ottawa Hospital Research Institute (CA)
Publication Details
- Journal
- Cancers
- Published
- 2025-10-14
- DOI
- https://doi.org/10.3390/cancers17203319
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00