β-Sitosterol attenuates obstructive sleep apnea-related myocardial injury via MALAT1-mediated HIF-1α regulation
<i>β-Sitosterol</i> attenuates CIH-induced myocardial injury by inhibiting the MALAT1/HIF-1α axis, suggesting its potential as a therapeutic agent for OSA patients with limited tolerance to conventional therapies.
Authors
- Jing Li (ORCID: https://orcid.org/0000-0001-9392-6600)
- Qin Chen (ORCID: https://orcid.org/0000-0002-0526-2005)
- Feng Wang (ORCID: https://orcid.org/0000-0001-7203-0098)
- Dan Liu (ORCID: https://orcid.org/0009-0001-8157-4908)
- Naijie Chen
- Runhua Wu
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-10-15
- DOI
- https://doi.org/10.3389/fphar.2025.1692758
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Fujian Province