Can patient-derived in vitro models improve clinical translation in critical care research when used before animal studies?
By harnessing the strengths of both model systems, this two-step strategy could help bridge the translational gap in critical care, improve therapeutic development, and accelerate precision medicine in sepsis and other critical illnesses.
Authors
- Raphaël Favory (ORCID: https://orcid.org/0000-0001-7772-2608)
- Sébastien Préau (ORCID: https://orcid.org/0000-0002-8638-7183)
- Alexandre Pierre (ORCID: https://orcid.org/0000-0001-5343-4599)
- Steve Lancel (ORCID: https://orcid.org/0000-0002-3292-5433)
Institutions
- Inserm (FR)
- Université de Lille (FR)
- Institut Pasteur de Lille (FR)
- Centre Hospitalier Universitaire de Lille (FR)
- Hôpital Roger Salengro (FR)
Publication Details
- Journal
- Intensive Care Medicine Experimental
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1186/s40635-025-00814-z
- Citations
- 1
- Primary Topic
- 3D Printing in Biomedical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.67
Funders
- Agence Nationale de la Recherche