Coexisting inflammatory bowel disease in primary sclerosing cholangitis is associated with higher colorectal cancer and transplant risk
Patients with coexisting IBD and PSC experience greater clinical severity, including higher mortality, hospitalization, and colorectal cancer risk. They also have increased liver transplant incidence. Further research is needed to explore underlying mechanisms and improve management.
Authors
- Nagesh Jadhav (ORCID: https://orcid.org/0000-0001-8993-3947)
- Kaiwen Zhu (ORCID: https://orcid.org/0000-0002-1734-2512)
- Asim Mushtaq (ORCID: https://orcid.org/0000-0003-2592-1562)
- Patrick Okolo (ORCID: https://orcid.org/0000-0003-0928-7303)
- Ebubekir Daglilar (ORCID: https://orcid.org/0000-0003-0622-1704)
- Jing Zhang (ORCID: https://orcid.org/0000-0002-4530-6754)
- Prajjwol Bhatta
Institutions
- Charleston Area Medical Center (US)
- Vancouver Hospital and Health Sciences Centre (CA)
- Rochester General Hospital (US)
Publication Details
- Journal
- Journal of Internal Medicine
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1111/joim.70026
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 0.00