Efficacy and safety of live combined Bacillus subtilis and Enterococcus faecium in patients with constipation: a meta-analysis of randomized controlled trials
LCBE demonstrates a favorable efficacy and good tolerability in patients with constipation. This meta-analysis provides supportive evidence for its clinical application in the management of constipation.
Authors
- Wenwen Li (ORCID: https://orcid.org/0000-0002-7295-0190)
- Xiaoqian Zhang (ORCID: https://orcid.org/0000-0002-5873-6497)
- Guangcai Li (ORCID: https://orcid.org/0009-0004-3243-0600)
- Dandan Yang (ORCID: https://orcid.org/0000-0003-3558-7166)
- Yingying Liang
Institutions
- Weifang Medical University (CN)
- Second Hospital of Shandong University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-10-15
- DOI
- https://doi.org/10.3389/fphar.2025.1688544
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shandong Province