Unveiling the Therapeutic Targets and Active Components of Xianlinggubao Capsule in Osteoarthritis and Osteoporosis through Network Pharmacology and Bioinformatics Analysis

This study has demonstrated that danshenxinkun B and miltirone may be pivotal agents in treating OA and OP by down-regulating the expressions of Ptgs2, Fos, and Tnfaip3.

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Publication Details

Journal
Current Pharmaceutical Design
Published
2025-10-08
DOI
https://doi.org/10.2174/0113816128406157250911093530
Primary Topic
Bone Metabolism and Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Unveiling the Therapeutic Targets and Active Components of Xianlinggubao Capsule in Osteoarthritis and Osteoporosis through Network Pharmacology and Bioinformatics Analysis

Qing Ma, Xuejiao Hua, Jianhui Liu, Xuhui Ma
Current Pharmaceutical Design
Bone Metabolism and Diseases
article

Unveiling the Therapeutic Targets and Active Components of Xianlinggubao Capsule in Osteoarthritis and Osteoporosis through Network Pharmacology and Bioinformatics Analysis

Qing Ma, Xuejiao Hua, Jianhui Liu, Xuhui Ma
article en

Abstract

This study has demonstrated that danshenxinkun B and miltirone may be pivotal agents in treating OA and OP by down-regulating the expressions of Ptgs2, Fos, and Tnfaip3.

Current Pharmaceutical DesignVol. 32
Chongqing University (CN), Chongqing University of Science and Technology (CN), Shanghai Ship and Shipping Research Institute (CN), Taiyuan Central Hospital (CN), Fourth People's Hospital of Taiyuan (CN), Chongqing University of Technology (CN)
Openalex Percentile: Top 74%
Bone Metabolism and Diseases
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