Computational Exploration of Flavonoids as HCV NS3/4A Protease Inhibitors: Advancing Antiviral Therapies to Mitigate Liver Cancer Risk

This investigation identifies 10 flavonoids with high potential as NS3/4A protease inhibitors, providing a basis for future biological validation and safer drug development.

Authors

Mohd Rehan (ORCID: https://orcid.org/0000-0003-4898-6043)
Eman Mahmoud

Institutions

King Abdulaziz University (SA)
King Abdullah Medical City (SA)

Publication Details

Journal: Current Pharmaceutical Design
Published: 2025-10-07
DOI: https://doi.org/10.2174/0113816128386884250904063752
Primary Topic: Hepatitis C virus research
Type: article
Field-Weighted Citation Impact: 0.00

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article

Computational Exploration of Flavonoids as HCV NS3/4A Protease Inhibitors: Advancing Antiviral Therapies to Mitigate Liver Cancer Risk

Mohd Rehan, Eman Mahmoud

Oct 7, 2025

Current Pharmaceutical Design

Hepatitis C virus research

article

Computational Exploration of Flavonoids as HCV NS3/4A Protease Inhibitors: Advancing Antiviral Therapies to Mitigate Liver Cancer Risk

Mohd Rehan, Eman Mahmoud

October 7, 2025article en

Abstract

This investigation identifies 10 flavonoids with high potential as NS3/4A protease inhibitors, providing a basis for future biological validation and safer drug development.

Current Pharmaceutical DesignVol. 32

King Abdulaziz University (SA), King Abdullah Medical City (SA)

Openalex Percentile: Top 61%

Hepatitis C virus research

DOI Source OpenAlex

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Computational Exploration of Flavonoids as HCV NS3/4A Protease Inhibitors: Advancing Antiviral Therapies to Mitigate Liver Cancer Risk — Mohd Rehan, Eman Mahmoud · Current Pharmaceutical Design (2025) | TGRS Research Map | TGRS