Advances in 3D Printing Technology for Orodispersible Tablets Represent a New Direction in Personalized Drug Delivery

ODTs are solid dosage forms that break down or dissolve quickly in the mouth without water. Orodispersible tablets(ODTs) have changed how we administer drugs, especially for children, elderly patients, and those who have difficulty swallowing. The arrival of 3D printing has improved the possibilitiesfor ODTs by allowing precise control over drug dosage, shape, and release profiles. Thissupportsthe idea of tailored therapy. The printed formulation meets patient goals by providing the right dose based on individual needs and drug release patterns. Recently, 3D printing has emerged in pharmaceutical development, offering a chance to move away from standardized medication dosing and toward more precise and personalized treatments. Many technologies have beendeveloped inthe pharmaceuticalfield, butfew offer the same advantages as 3D printing. This review looks at the latest advancements in 3D printing techniques for creating ODTs. It emphasizes different printing methods, formulation strategies, excipient choices, and regulatory issues. The article also discusses the challenges and future paths for clinical use and commercial implementation.

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Publication Details

Published
2025-10-15
DOI
https://doi.org/10.38124/ijisrt/25oct523
Primary Topic
3D Printing in Biomedical Research
Type
article
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article

Advances in 3D Printing Technology for Orodispersible Tablets Represent a New Direction in Personalized Drug Delivery

Velmurugan Balasubramanian, J. Jayabalan, Manimozhi Kumaraswamy, Anmol Kumar et al.
3D Printing in Biomedical Research
article

Advances in 3D Printing Technology for Orodispersible Tablets Represent a New Direction in Personalized Drug Delivery

Velmurugan Balasubramanian, J. Jayabalan, Manimozhi Kumaraswamy, Anmol Kumar, Gokul Sathasivam, Rubasri Asaithambi
article en

Abstract

ODTs are solid dosage forms that break down or dissolve quickly in the mouth without water. Orodispersible tablets(ODTs) have changed how we administer drugs, especially for children, elderly patients, and those who have difficulty swallowing. The arrival of 3D printing has improved the possibilitiesfor ODTs by allowing precise control over drug dosage, shape, and release profiles. Thissupportsthe idea of tailored therapy. The printed formulation meets patient goals by providing the right dose based on individual needs and drug release patterns. Recently, 3D printing has emerged in pharmaceutical development, offering a chance to move away from standardized medication dosing and toward more precise and personalized treatments. Many technologies have beendeveloped inthe pharmaceuticalfield, butfew offer the same advantages as 3D printing. This review looks at the latest advancements in 3D printing techniques for creating ODTs. It emphasizes different printing methods, formulation strategies, excipient choices, and regulatory issues. The article also discusses the challenges and future paths for clinical use and commercial implementation.

Openalex Percentile: Top 72%
3D Printing in Biomedical Research
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