M2-exo promote orthodontic bone remodeling via the MeCP2-TCF20-HDAC1 axis
These findings highlight the critical role of the M2-exo/MeCP2-TCF20 axis in orchestrating orthodontic bone remodeling through epigenetic regulation. This study provides novel insights into the therapeutic potential of M2-exos for enhancing orthodontic treatment efficiency.
Authors
- Guangyu Bao
- Liya Ma
- Yanjie Li (ORCID: https://orcid.org/0009-0003-9753-2635)
- Mingzhu Chen (ORCID: https://orcid.org/0000-0002-1183-7688)
- Junxiong Li (ORCID: https://orcid.org/0000-0002-1951-2589)
- Zhen-jin Yang
- Mengting Chen
- Jiangtian Hu (ORCID: https://orcid.org/0009-0007-2747-2509)
Institutions
- Yunnan University (CN)
- Kunming Medical University (CN)
- Stomatology Hospital (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1186/s13287-025-04633-7
- Citations
- 1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China
- Kunming Medical University