The role of insulin resistance in the longitudinal progression from NAFLD to cardiovascular-kidney-metabolic disease
Insulin resistance independently accelerated the progression from NAFLD to CKM diseases, particularly ischemic stroke. Healthy sleep and regular physical activity failed to offset this detrimental impact.
Authors
- Min Peng (ORCID: https://orcid.org/0000-0002-9744-338X)
- Chao Hou (ORCID: https://orcid.org/0000-0003-3855-1660)
- Dahong Yang (ORCID: https://orcid.org/0000-0002-8189-0791)
- Xuan Shi (ORCID: https://orcid.org/0000-0002-5525-3561)
- Fang Wang (ORCID: https://orcid.org/0000-0002-6674-5537)
- Xiaomei Yuan (ORCID: https://orcid.org/0000-0002-8248-5405)
- Ke Song (ORCID: https://orcid.org/0000-0002-0156-3185)
- Jianzhong Shi (ORCID: https://orcid.org/0000-0003-4580-9455)
- Gelin Xu
Institutions
- Guangxi University (CN)
- Army Medical University (CN)
- Nanjing General Hospital of Nanjing Military Command (CN)
- Nanjing Drum Tower Hospital (CN)
- Guangxi University of Chinese Medicine (CN)
- Xinqiao Hospital (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Liuyang City Maternal and Child Health Hospital (CN)
- Shaoxing People's Hospital (CN)
- Shenzhen Second People's Hospital (CN)
- Nanjing Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1186/s12933-025-02953-9
- Citations
- 4
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 5.42
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation