Serum vesicle biomarkers reflect the disease activity of idiopathic pulmonary fibrosis
Serum extracellular vesicles could capture heterogenetic fibrotic profiles in IPF, and SFTPB can be a promising biomarker reflecting the disease activity.
Authors
- Shinji Futami
- Yoshikazu Inoue (ORCID: https://orcid.org/0000-0003-3994-874X)
- Soichiro Funaki (ORCID: https://orcid.org/0000-0003-2386-4736)
- Naoko Ose (ORCID: https://orcid.org/0000-0002-3509-9536)
- M Itoh (ORCID: https://orcid.org/0000-0001-7917-2830)
- Atsushi Kumanogoh (ORCID: https://orcid.org/0000-0003-4749-7117)
- Yujiro Naito
- Shohei Koyama (ORCID: https://orcid.org/0000-0002-6897-9417)
- Yasuhiko Suga (ORCID: https://orcid.org/0000-0002-4906-8810)
- Taro Koba (ORCID: https://orcid.org/0000-0001-7715-9042)
- Kentaro Masuhiro (ORCID: https://orcid.org/0000-0002-8785-1726)
- Yukinori Okada (ORCID: https://orcid.org/0000-0002-0311-8472)
- Kota Iwahori (ORCID: https://orcid.org/0000-0002-9891-6003)
- Izumi Nagatomo (ORCID: https://orcid.org/0000-0001-5382-4327)
- Shigeyuki Shichino (ORCID: https://orcid.org/0000-0002-1683-2448)
- Kiyoharu Fukushima (ORCID: https://orcid.org/0000-0002-9767-7899)
- Satoshi Nojima (ORCID: https://orcid.org/0000-0002-5124-0026)
- Takeshi Tomonaga
- Yuichi Adachi (ORCID: https://orcid.org/0000-0002-8867-3191)
- Ryuya Edahiro (ORCID: https://orcid.org/0000-0001-5009-6408)
- Jun Adachi
- Hanako Yoshimura (ORCID: https://orcid.org/0000-0002-3717-3963)
- Kenji Mizuguchi (ORCID: https://orcid.org/0000-0003-3021-7078)
- Takatoshi Enomoto (ORCID: https://orcid.org/0000-0002-1771-6684)
- Yoshito Takeda (ORCID: https://orcid.org/0000-0003-2905-6537)
- Reina Hara (ORCID: https://orcid.org/0000-0001-7013-4328)
- Yasushi Shintani (ORCID: https://orcid.org/0000-0002-2540-5288)
- Daisuke Nakatsubo (ORCID: https://orcid.org/0009-0004-0517-0874)
- Saori Amiya
- Yoshimi Noda
- Yu Futami (ORCID: https://orcid.org/0000-0002-1665-3474)
- Mana Nakayama
- Yayoi Natsume‐Kitatani (ORCID: https://orcid.org/0000-0003-1749-3318)
- Maiko Naito (ORCID: https://orcid.org/0000-0002-4360-7043)
- Kotaro Miyake (ORCID: https://orcid.org/0000-0002-6441-1699)
- Masahiro Yanagawa (ORCID: https://orcid.org/0000-0002-0911-6769)
- Yuya Shirai (ORCID: https://orcid.org/0000-0002-0518-9020)
- Haruhiko Hirata (ORCID: https://orcid.org/0000-0002-1134-7283)
- T. Matsuki (ORCID: https://orcid.org/0000-0002-4416-6083)
- Takayuki Shiroyama (ORCID: https://orcid.org/0000-0002-2816-9428)
- Takahiro Kawasaki (ORCID: https://orcid.org/0000-0002-8625-7899)
- Miho Takahashi-Itoh
- Makoto Yamamoto
Institutions
- Osaka Gakuin University (JP)
- Tokyo University of Science (JP)
- Japan Agency for Medical Research and Development (JP)
- National Institute of Biomedical Innovation, Health and Nutrition (JP)
- Toneyama National Hospital (JP)
- Kinki Central Hospital (JP)
- National Hospital Organization (JP)
- RIKEN Center for Integrative Medical Sciences (JP)
- Protein Research Foundation (JP)
- NHO Kinki Chuo Chest Medical Center (JP)
- Osaka International University (JP)
- The University of Tokyo (JP)
- Tokushima University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1186/s12967-025-07011-2
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Agency for Medical Research and Development
- Japanese Respiratory Foundation
- Cabinet Office, Government of Japan
- Ministry of Health, Labour and Welfare
- Japan Society for the Promotion of Science