Performance evaluation of alternative bacteriological measures of response to MDR/RR-TB therapy during the initial 16 weeks of treatment
Our data show that concentrated Fluorescent smear, Fluorescein-di-acetate smear microscopy, and TB-MBLA are suitable alternative measures of response to TB therapy compared to MGIT culture among MDR-TB participants. Use of these alternative rapid methods may allow timely decision making as well as rapid evaluation of alternative MDR-TB treatment regimens.
Authors
- Achilles Katamba (ORCID: https://orcid.org/0000-0002-2347-4183)
- Willy Ssengooba (ORCID: https://orcid.org/0000-0002-1643-110X)
- Christine Sekaggya‐Wiltshire (ORCID: https://orcid.org/0000-0001-9247-2950)
- Emmanuel Musisi (ORCID: https://orcid.org/0000-0001-7229-195X)
- Derek J. Sloan (ORCID: https://orcid.org/0000-0002-7888-5449)
- Kevin Komakech
- Mohammed Lamorde (ORCID: https://orcid.org/0000-0003-2218-6822)
- Susan Adakun
- Derrick Semugenze
- Moses Lutaakome Joloba (ORCID: https://orcid.org/0000-0002-0334-9983)
- Moses Ndema
- Wilber Sabiiti
Institutions
- University of St Andrews (GB)
- Mulago Hospital (UG)
- Infectious Diseases Institute (UG)
- Naguru General Hospital (UG)
- Makerere University (UG)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1186/s12879-025-11785-7
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00