Prognostic significance of baseline skeletal muscle index and its dynamics in patients with metastatic breast cancer undergoing eribulin treatment
Baseline SMI and PNI provide complementary prognostic information in patients with MBC receiving eribulin. Furthermore, on-treatment SMI gain, but not PNI increase, was associated with improved survival. Monitoring and enhancing skeletal muscle mass may improve outcomes, highlighting the importance of integrating supportive care strategies during chemotherapy.
Authors
- H. Morikawa (ORCID: https://orcid.org/0009-0002-8288-6628)
- Masatsugu Amitani
- Ken‐ichi Ito (ORCID: https://orcid.org/0000-0002-6430-0307)
- Nami Kiyosawa
- Tadafumi Shimizu (ORCID: https://orcid.org/0000-0001-6965-8781)
- Mayu Ono
- Ryoko Iji
- Toshiharu Kanai
- Tatsunori Chino
- Takaaki Oba (ORCID: https://orcid.org/0000-0001-8283-4989)
- Shinsuke Katsuyama
- Ayaka Kitazawa
Institutions
- Shinshu University (JP)
- Shinshu University Hospital (JP)
Publication Details
- Journal
- Breast Cancer Research and Treatment
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1007/s10549-025-07827-y
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00