Extracellular vesicles derived from menstrual blood-derived mesenchymal stem cells suppress inflammatory atherosclerosis by inhibiting NF-κB signaling
This study reveals that the engineering of EVs derived from MenSCs holds significant promise as a strategic clinical approach for addressing inflammatory atherosclerosis.
Authors
- Jiuwei Yu (ORCID: https://orcid.org/0000-0002-8619-7662)
- Xinxing Zhu (ORCID: https://orcid.org/0000-0002-8705-0013)
- Lele Jin
- Chunfu Zheng (ORCID: https://orcid.org/0000-0002-8797-1322)
- Emmanuel Jairaj Moses (ORCID: https://orcid.org/0000-0003-2939-8473)
- Hongxia Wang (ORCID: https://orcid.org/0000-0003-3481-6940)
- Yong Zhang (ORCID: https://orcid.org/0000-0002-1303-0458)
- Han Li (ORCID: https://orcid.org/0000-0002-2097-5572)
- Chao Shi (ORCID: https://orcid.org/0000-0002-3808-8699)
- Hongxing Zhang (ORCID: https://orcid.org/0009-0008-5178-3021)
- Yongwei Yang (ORCID: https://orcid.org/0000-0002-0145-1562)
- Jie Lian (ORCID: https://orcid.org/0000-0003-4351-2164)
- Suhui Wang
- Haihui Li (ORCID: https://orcid.org/0000-0002-8475-4875)
- Xilian Chen (ORCID: https://orcid.org/0000-0003-4613-0890)
- Xiaotian Liu (ORCID: https://orcid.org/0000-0002-1761-2631)
- Yingke Li (ORCID: https://orcid.org/0000-0002-8727-5650)
Institutions
- Universiti Sains Malaysia (MY)
- University of Calgary (CA)
- Bengbu Medical College (CN)
- Hospital Universiti Sains Malaysia (MY)
- Heze Municipal Hospital (CN)
- Yantaishan Hospital (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
- Henan Medical University (CN)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1186/s12916-025-04390-7
- Citations
- 19
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 15.31