Identification and validation of aryl hydrocarbon receptor-associated hub genes in ulcerative colitis via integrated bioinformatics analysis
PPARG, IL1B, and IDO1 were identified as potential key genes closely associated with AHR, suggesting their possible involvement in modulating AhR signaling in UC, thereby offering a theoretical basis for disease diagnosis and therapeutic strategies.
Authors
- Fuqiong Jiang (ORCID: https://orcid.org/0000-0002-8207-2838)
- Yichen Hu (ORCID: https://orcid.org/0000-0002-0720-583X)
- Yuanpei Zhao (ORCID: https://orcid.org/0000-0003-4215-9522)
- Wenliang Li (ORCID: https://orcid.org/0000-0002-4219-9770)
- Weiming Li (ORCID: https://orcid.org/0000-0001-9220-514X)
- Hongyuan Liu (ORCID: https://orcid.org/0000-0002-1324-0842)
- Jiaping Wang (ORCID: https://orcid.org/0000-0002-7143-6851)
- Kaiwen Shi (ORCID: https://orcid.org/0000-0002-7688-6018)
- Xiao‐Li Min (ORCID: https://orcid.org/0009-0009-1025-8041)
Institutions
- Kunming Medical University (CN)
Publication Details
- Journal
- Human Genomics
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1186/s40246-025-00835-5
- Citations
- 1
- Primary Topic
- Vitamin D Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- National Natural Science Foundation of China
- Kunming Medical University