Glutamic acid-lysine (EK) rich motif of RabD2 self-associates and regulates adhesion through multivesicular bodies in Entamoeba histolytica
Thus, amoebic RabD2 is a new class of Rab protein that forms high-ordered self-association variants and controls adhesion to the host cells, which impacts the pathogenesis of E. histolytica through the biogenesis of MVBs.
Authors
- Navyaka Padavala
Institutions
- Centre for DNA Fingerprinting and Diagnostics (IN)
Publication Details
- Journal
- BMC Biology
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1186/s12915-025-02415-4
- Primary Topic
- Amoebic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Arthritis National Research Foundation
- National Research Foundation
- Department of Biotechnology, Ministry of Science and Technology, India
- Indian Institute of Science Education and Research Mohali
- Nirma University
- Science and Engineering Research Board
- Centre for DNA Fingerprinting and Diagnostics