Vaccine-induced immunity is maintained in glioma patients relative to other solid tumours
This study demonstrates that glioma patients can mount meaningful immune responses to DNA and mRNA vaccines, suggesting that glioma-based vaccine therapies are feasible and warrant further exploration.
Authors
- Malinda Itchins (ORCID: https://orcid.org/0000-0002-2741-8250)
- Razia Zakarya (ORCID: https://orcid.org/0000-0002-9259-9369)
- Kelly J. McKelvey (ORCID: https://orcid.org/0000-0002-4923-791X)
- Alexander Guminski (ORCID: https://orcid.org/0000-0003-3681-7015)
- Alexander Maxwell Menzies (ORCID: https://orcid.org/0000-0001-5183-7562)
- Joe Wei (ORCID: https://orcid.org/0000-0003-1944-1079)
- Nick Pavlakis
- Ananda Prasanna Jagadeesan
- David Lok Hang Chan (ORCID: https://orcid.org/0000-0002-7773-3144)
- Muhammad Hafiznur Yunus (ORCID: https://orcid.org/0000-0001-9391-1548)
- Janice F. Gilson
- Adrian V. Lee (ORCID: https://orcid.org/0000-0001-9917-514X)
- Connie I. Diakos (ORCID: https://orcid.org/0000-0002-8877-3440)
- O. Zhang
- Amanda L. Hudson (ORCID: https://orcid.org/0000-0002-8275-0395)
- Michael Back (ORCID: https://orcid.org/0000-0003-2363-8333)
- Dasantha Jayamanne (ORCID: https://orcid.org/0000-0002-5363-3974)
- Emily K. Colvin (ORCID: https://orcid.org/0000-0002-5435-5902)
- Shihani Stoner
- Marina Kastelan (ORCID: https://orcid.org/0000-0003-4866-4124)
- Alexander Yuile (ORCID: https://orcid.org/0000-0002-7242-0528)
- Thomas Eade (ORCID: https://orcid.org/0000-0003-4324-1886)
- Hasanthi C. de Silva
- Helen Wheeler (ORCID: https://orcid.org/0000-0002-6949-354X)
- Andrew Kneebone (ORCID: https://orcid.org/0000-0002-7629-504X)
- Lionel Leck
- Meredith Oatley (ORCID: https://orcid.org/0000-0002-2644-5695)
- Laila Arzuman
Institutions
- The University of Sydney (AU)
- Royal North Shore Hospital (AU)
- Prince of Wales Hospital (AU)
- Melanoma Institute Australia (AU)
- Northern Sydney Local Health District (AU)
Publication Details
- Journal
- Journal of Neuro-Oncology
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1007/s11060-025-05258-9
- Citations
- 1
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- Hunter Medical Research Institute