Identification and validation of selenium metabolism-related genes in lung adenocarcinoma prognosis using bioinformatics analysis

This study identified four prognostic genes in LUAD and examined their associated mechanisms of action, which may contribute to the development of novel treatment strategies. The integration of immune characterization with drug sensitivity analysis offers valuable insights for stratified therapy.

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Publication Details

Journal
Frontiers in Genetics
Published
2025-10-15
DOI
https://doi.org/10.3389/fgene.2025.1655262
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Identification and validation of selenium metabolism-related genes in lung adenocarcinoma prognosis using bioinformatics analysis

Shuai Shen, Yang Wang, Zheyuan Xu, Yun Chen et al.
Frontiers in Genetics
Ferroptosis and cancer prognosis
article

Identification and validation of selenium metabolism-related genes in lung adenocarcinoma prognosis using bioinformatics analysis

Shuai Shen, Yang Wang, Zheyuan Xu, Yun Chen, Ping Li, Ni Chen, Hao Peng
article en

Abstract

This study identified four prognostic genes in LUAD and examined their associated mechanisms of action, which may contribute to the development of novel treatment strategies. The integration of immune characterization with drug sensitivity analysis offers valuable insights for stratified therapy.

Frontiers in GeneticsVol. 16
Kunming University of Science and Technology (CN), Kunming Medical University (CN), First People's Hospital of Yunnan Province (CN), The First Hospital of Kunming (CN), First Affiliated Hospital of Kunming Medical University (CN)
Openalex Percentile: Top 58%
Ferroptosis and cancer prognosis
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