<i>Off-label</i> Use of Gastrointestinal Multiplex PCR Panel for the Diagnosis of Amoebic Liver Abscess: A Three-case Pediatric Report

Diagnosis of amoebic liver abscess is challenging. A multiplex polymerase chain reaction panel, traditionally employed for the detection of enteric pathogens in stool, proved useful for the rapid diagnosis in 3 pediatric patients when used off-label on liver abscess fluid. While this approach enabled timely and targeted antiamoebic therapy, highlighting its potential in high-burden, resource-limited settings, it represents an unvalidated use of the technology that requires further investigation.