Hashimoto's thyroiditis and congenital long QT syndrome: a dangerous addition causing torsades—case report

Hypothyroidism is linked to electrocardiographic abnormalities such as sinus bradycardia, QT interval prolongation, malignant ventricular arrhythmias such as ventricular premature beat, ventricular tachycardia, TdP, and ventricular fibrillation. Assessment of thyroid function is of high value in QT prolongation syndromes to avoid SCD incidence. Thyroid hormone influences ventricular inhomogeneity, and L-thyroxine replacement treatment may minimize malignant ventricular arrhythmia and sudden cardiac death in patients with primary hypothyroidism. Our case highlights the importance of urgent electrolyte replacement and levothyroxine therapy to avoid the risk of ventricular arrhythmias.

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Publication Details

Journal
European Heart Journal - Case Reports
Published
2025-10-14
DOI
https://doi.org/10.1093/ehjcr/ytaf504
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Hashimoto's thyroiditis and congenital long QT syndrome: a dangerous addition causing torsades—case report

Byomesh Tripathi, Ramesh Acharya, Deepti Pandit, Dan Schuller et al.
European Heart Journal - Case Reports
Thyroid Disorders and Treatments
article

Hashimoto's thyroiditis and congenital long QT syndrome: a dangerous addition causing torsades—case report

Byomesh Tripathi, Ramesh Acharya, Deepti Pandit, Dan Schuller, Vaishnavi Sabesan
article en

Abstract

Hypothyroidism is linked to electrocardiographic abnormalities such as sinus bradycardia, QT interval prolongation, malignant ventricular arrhythmias such as ventricular premature beat, ventricular tachycardia, TdP, and ventricular fibrillation. Assessment of thyroid function is of high value in QT prolongation syndromes to avoid SCD incidence. Thyroid hormone influences ventricular inhomogeneity, and L-thyroxine replacement treatment may minimize malignant ventricular arrhythmia and sudden cardiac death in patients with primary hypothyroidism. Our case highlights the importance of urgent electrolyte replacement and levothyroxine therapy to avoid the risk of ventricular arrhythmias.

European Heart Journal - Case ReportsVol. 9(11)
Texas Tech University (US), The University of Texas at El Paso (US), University Medical Center of El Paso (US), KIST Medical College (NP)
Openalex Percentile: Top 61%
Thyroid Disorders and Treatments
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Hashimoto's thyroiditis and congenital long QT syndrome: a dangerous addition causing torsades—case report — Byomesh Tripathi, Ramesh Acharya, et al. · European Heart Journal - Case Reports (2025) | TGRS Research Map | TGRS