Synthesis of thiazoles by desulfurative cyclization/ring expansion cascade reaction of <i>S</i> -azirinyl xanthates: two mechanistically distinct radical pathways
Alkyl and silyl radicals react with S -azirinyl xanthates at the nitrogen atom, while stannyl radicals – at the sulfur atom, leading in two different ways to the formation of azirine ring expansion products, 2-alkoxythiazole-5-carboxylic esters.
Authors
- Alexander F. Khlebnikov (ORCID: https://orcid.org/0000-0002-6100-0309)
- Николай В. Ростовский (ORCID: https://orcid.org/0000-0002-8925-794X)
- Anastasiya V. Agafonova (ORCID: https://orcid.org/0000-0003-1855-7440)
- Dmitrii Sergeevich Vasilchenko
- Михаил С. Новиков (ORCID: https://orcid.org/0000-0001-5106-4723)
Institutions
- St Petersburg University (RU)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1039/d5qo01233c
- Primary Topic
- Synthesis and Catalytic Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00