Association of Remnant Cholesterol with Platelet Reactivity in Coronary Artery Disease Patients Receiving PCI

In the large-scale (n = 6,633) and real-world study, we revealed that RC may modify the platelet reactivity to influence the risk of bleeding and ischemia in PCI patients. Our study firstly reported the relationship between RC and clopidogrel-related platelet reactivity in patients undergoing PCI received dual antiplatelet therapy. The findings may verify the complex interaction between lipid and thrombosis and suggest that RC may be a potential marker associated with platelet reactivity, which warrants further investigation in future studies.

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Publication Details

Journal
Global Heart
Published
2025-10-15
DOI
https://doi.org/10.5334/gh.1475
Primary Topic
Antiplatelet Therapy and Cardiovascular Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of Remnant Cholesterol with Platelet Reactivity in Coronary Artery Disease Patients Receiving PCI

Jiawen Li, Kexin Zhang, Pei Zhu
Global Heart
Antiplatelet Therapy and Cardiovascular Diseases
article

Association of Remnant Cholesterol with Platelet Reactivity in Coronary Artery Disease Patients Receiving PCI

Jiawen Li, Kexin Zhang, Pei Zhu
article en

Abstract

In the large-scale (n = 6,633) and real-world study, we revealed that RC may modify the platelet reactivity to influence the risk of bleeding and ischemia in PCI patients. Our study firstly reported the relationship between RC and clopidogrel-related platelet reactivity in patients undergoing PCI received dual antiplatelet therapy. The findings may verify the complex interaction between lipid and thrombosis and suggest that RC may be a potential marker associated with platelet reactivity, which warrants further investigation in future studies.

Global HeartVol. 20(1)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Fu Wai Hospital (CN)
Openalex Percentile: Top 56%
Antiplatelet Therapy and Cardiovascular Diseases
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