Inositol metabolism shapes tumor aggressiveness and immune evasion in lower-grade glioma: an integrative analysis of bulk, single-cell, and spatial transcriptomics

Inositol metabolism status serves as a potent prognostic biomarker in LGG, intricately linked to tumor aggressiveness and immune evasion, highlighting its potential as a therapeutic target.

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Publication Details

Journal
International Journal of Surgery
Published
2025-10-13
DOI
https://doi.org/10.1097/js9.0000000000003604
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Inositol metabolism shapes tumor aggressiveness and immune evasion in lower-grade glioma: an integrative analysis of bulk, single-cell, and spatial transcriptomics

Qian Chen, Liangfang Shen, Dongfeng Deng, Shan Li
International Journal of Surgery
Ferroptosis and cancer prognosis
article

Inositol metabolism shapes tumor aggressiveness and immune evasion in lower-grade glioma: an integrative analysis of bulk, single-cell, and spatial transcriptomics

Qian Chen, Liangfang Shen, Dongfeng Deng, Shan Li
article en

Abstract

Inositol metabolism status serves as a potent prognostic biomarker in LGG, intricately linked to tumor aggressiveness and immune evasion, highlighting its potential as a therapeutic target.

International Journal of SurgeryVol. 112(2)
Huaihua University (CN), Central South University (CN), Xiangya Hospital Central South University (CN)
Openalex Percentile: Top 58%
Ferroptosis and cancer prognosis
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