Incidence and Survival of IDH-Wildtype Glioblastoma and IDH-Mutant Astrocytoma by Treatment and Sex: A Regional Study in Spain (2011–2021)
IDH-wildtype glioblastoma shows persistently poor outcomes despite increasing incidence, while IDH-mutant astrocytoma demonstrates better survival, particularly in male patients and those receiving multimodal therapy. These findings reflect real-world practice and provide epidemiological and survival data from Southern Europe to guide future clinical and public health strategies.
Authors
- Eduardo I. Cardenas (ORCID: https://orcid.org/0000-0001-5973-5675)
- Juan Antonio Encarnación (ORCID: https://orcid.org/0000-0003-1463-9326)
- Ana Cristina Manso (ORCID: https://orcid.org/0000-0002-9881-3338)
- Macarena I. de la Fuente
- Mario Royo-Villanova (ORCID: https://orcid.org/0000-0002-2898-2312)
- Pedro Ruiz (ORCID: https://orcid.org/0000-0001-6194-672X)
- Silverio Ros (ORCID: https://orcid.org/0009-0008-8616-2401)
- José Luis Alonso-Romero (ORCID: https://orcid.org/0000-0001-8746-2096)
Institutions
- Hospital Universitario Virgen de la Arrixaca (ES)
- Universidad de Murcia (ES)
Publication Details
- Journal
- Medical Sciences
- Published
- 2025-10-14
- DOI
- https://doi.org/10.3390/medsci13040233
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00