From Incision to Immunity: Integrating Surgery and Immunotherapy in Non-Small Cell Lung Cancer

Lung cancer is the most common cause of death due to cancer in the world, and non-small cell lung cancer (NSCLC) is the most common form of lung cancer, representing approximately 84% of all cases. Due to its frequency and mortality, the amount of research on this subject has been greatly increased and new techniques to improve health outcomes have been established. While surgery remains the gold standard of treatment, immunotherapy used alone or in conjunction with surgery shows promising results. This review aims to give an overview of current and new surgical and immunotherapy methods used for the treatment of NSCLC, as well as ways in which they can be combined and the clinical outcomes for patients with each treatment modality. Additionally, it will seek to highlight any gaps in current knowledge of treatment and propose further studies to improve the efficacy of NSCLC treatments.

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Publication Details

Journal
Immuno
Published
2025-10-14
DOI
https://doi.org/10.3390/immuno5040048
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00

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From Incision to Immunity: Integrating Surgery and Immunotherapy in Non-Small Cell Lung Cancer

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Cancer Immunotherapy and Biomarkers
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From Incision to Immunity: Integrating Surgery and Immunotherapy in Non-Small Cell Lung Cancer

Mark R. Wakefield, Yujiang Fang, Michael Ann Janes, Aidan A. Schmidt, Ashvin Chouhan, Garret A. Krieg
article en

Abstract

Lung cancer is the most common cause of death due to cancer in the world, and non-small cell lung cancer (NSCLC) is the most common form of lung cancer, representing approximately 84% of all cases. Due to its frequency and mortality, the amount of research on this subject has been greatly increased and new techniques to improve health outcomes have been established. While surgery remains the gold standard of treatment, immunotherapy used alone or in conjunction with surgery shows promising results. This review aims to give an overview of current and new surgical and immunotherapy methods used for the treatment of NSCLC, as well as ways in which they can be combined and the clinical outcomes for patients with each treatment modality. Additionally, it will seek to highlight any gaps in current knowledge of treatment and propose further studies to improve the efficacy of NSCLC treatments.

ImmunoVol. 5(4)
Peking University (CN), Peking University Third Hospital (CN), University of Missouri (US), Des Moines University (US)
Institute of Engineering Research, Seoul National University
Openalex Percentile: Top 61%
Cancer Immunotherapy and Biomarkers
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