<i>Photinia glabra</i> -derived exosome-like nanovesicles mitigate skin inflammaging via dual regulation of inflammatory signaling and calcium homeostasis
PgELNs mitigate skin inflammaging by dual regulation of inflammation and calcium homeostasis. Targeting the STAT1-CXCL9/10 axis, PgELNs reduce senescence and preserve barrier integrity. These findings highlight PgELNs as a promising plant-derived nanotherapeutic for managing inflammation-associated skin aging.
Authors
- Ki-Sun Park (ORCID: https://orcid.org/0000-0003-1322-767X)
- Yousang Jo (ORCID: https://orcid.org/0000-0001-8103-4998)
- Hyungjun Kim (ORCID: https://orcid.org/0000-0001-7997-7663)
- Kang-In Lee
- Hye Jin Kim (ORCID: https://orcid.org/0000-0001-9833-4751)
Institutions
- Korea Institute of Oriental Medicine (KR)
Publication Details
- Journal
- Nanomedicine
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1080/17435889.2025.2572991
- Citations
- 1
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81