GPR65 as a Laryngeal Cancer Risk Gene Identified through Single-Cell Transcriptomics, Mendelian Randomization Analysis, and Experimental Validation

The present findings showed that highly expressed GPR65 was a tumor-promoting gene in laryngeal cancer, showing its clinical value as a potential therapeutic target.

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Publication Details

Journal
Anti-Cancer Agents in Medicinal Chemistry
Published
2025-10-15
DOI
https://doi.org/10.2174/0118715206414176250905114930
Primary Topic
Cancer-related molecular mechanisms research
Type
article
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article

GPR65 as a Laryngeal Cancer Risk Gene Identified through Single-Cell Transcriptomics, Mendelian Randomization Analysis, and Experimental Validation

Haosheng Ni, Yuan‐Fei Zhou, Bin Zhao, Shu-Zheng Wang et al.
Anti-Cancer Agents in Medicinal Chemistry
Cancer-related molecular mechanisms research
article

GPR65 as a Laryngeal Cancer Risk Gene Identified through Single-Cell Transcriptomics, Mendelian Randomization Analysis, and Experimental Validation

Haosheng Ni, Yuan‐Fei Zhou, Bin Zhao, Shu-Zheng Wang, Qiao Mao, Hao Wu, Zhenxin Zhang
article en

Abstract

The present findings showed that highly expressed GPR65 was a tumor-promoting gene in laryngeal cancer, showing its clinical value as a potential therapeutic target.

Anti-Cancer Agents in Medicinal ChemistryVol. 26(2)
Nantong University (CN), Affiliated Hospital of Nantong University (CN)
Openalex Percentile: Top 64%
Cancer-related molecular mechanisms research
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