Hybrid CNN–Transformer with Fusion Discriminator for Ovarian Tumor Ultrasound Imaging Classification

We propose a local–global attention fusion network for benign–malignant discrimination of ovarian tumors in color Doppler ultrasound (CDFI). The framework integrates three complementary modules: a local enhancement module (LEM) to capture fine-grained texture and boundary cues, a Global Attention Module (GAM) to model long-range dependencies with flow-aware priors, and a Fusion Discriminator (FD) to align and adaptively reweight heterogeneous evidence for robust decision-making. The method was evaluated on a multi-center clinical dataset comprising 820 patient cases (482 benign and 338 malignant), ensuring a realistic and moderately imbalanced distribution. Compared with classical baselines including ResNet-50, DenseNet-121, ViT, Hybrid CNN–Transformer, U-Net, and SegNet, our approach achieved an accuracy of 0.923, sensitivity of 0.911, specificity of 0.934, AUC of 0.962, and F1-score of 0.918, yielding improvements of about three percentage points in the AUC and F1-score over the strongest baseline. Ablation experiments confirmed the necessity of each module, with the performance degrading notably when the GAM or the LEM was removed, while the complete design provided the best results, highlighting the benefit of local–global synergy. Five-fold cross-validation further demonstrated stable generalization (accuracy: 0.922; AUC: 0.961). These findings indicate that the proposed system offers accurate and robust assistance for preoperative triage, surgical decision support, and follow-up management of ovarian tumors.