Electrochemical skin conductance is associated with peripheral tissue hypoperfusion in septic patients
Electrochemical skin conductance measured via Sudoscan<sup>®</sup> may serve as a surrogate marker of autonomic sympathetic hyperactivation during sepsis and is associated with peripheral circulatory impairment. Although admission values were not independently predictive of mortality, elevated and persistently high Sudoscores are associated with death at day 28. Sudoscan<sup>®</sup> may offer a non-invasive window into sympathetic activity during septic shock and warrants further investigations.
Authors
- Tomas Urbina (ORCID: https://orcid.org/0000-0002-3745-9427)
- Lisa Raia
- Louaï Missri
- Hafid Ait‐Oufella (ORCID: https://orcid.org/0000-0002-2955-0183)
- Jean-Luc Baudel
- Jérémie Joffre (ORCID: https://orcid.org/0000-0003-4465-8392)
- Vincent Bonny (ORCID: https://orcid.org/0000-0002-8996-8426)
- J J Bernier
- Éric Maury (ORCID: https://orcid.org/0000-0002-7287-8694)
Institutions
- Inserm (FR)
- Sorbonne Université (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Paris Cardiovascular Research Center (FR)
- Centre de Recherche Saint-Antoine (FR)
Publication Details
- Journal
- Intensive Care Medicine Experimental
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1186/s40635-025-00813-0
- Primary Topic
- Heart Rate Variability and Autonomic Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00