Nitrosative Stress, Mitochondrial Peptides, and Ferroptosis Markers in Corneal Epithelial Cells from Keratoconus Patients

This is the first study to show that humanin and mitochondrial open-reading frame of the 12S rRNA-c can participate in the pathophysiology of keratoconus. In addition to the mitochondrial peptides, our data suggest that increased nitrosative stress and ferroptosis may contribute to the pathophysiology of keratoconus.

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Publication Details

Journal
Current Eye Research
Published
2025-10-14
DOI
https://doi.org/10.1080/02713683.2025.2570815
Citations
1
Primary Topic
Air Quality and Health Impacts
Type
article
Field-Weighted Citation Impact
1.20
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article

Nitrosative Stress, Mitochondrial Peptides, and Ferroptosis Markers in Corneal Epithelial Cells from Keratoconus Patients

Abdullah Tuncay Demiryürek, Ahmet Saracaloğlu, Antonio Mete, Şeniz Demiryürek et al.
1 citations
Current Eye Research
Air Quality and Health Impacts
1.20
article

Nitrosative Stress, Mitochondrial Peptides, and Ferroptosis Markers in Corneal Epithelial Cells from Keratoconus Patients

Abdullah Tuncay Demiryürek, Ahmet Saracaloğlu, Antonio Mete, Şeniz Demiryürek, Cahit Demirkiran
article en
1 citations

Abstract

This is the first study to show that humanin and mitochondrial open-reading frame of the 12S rRNA-c can participate in the pathophysiology of keratoconus. In addition to the mitochondrial peptides, our data suggest that increased nitrosative stress and ferroptosis may contribute to the pathophysiology of keratoconus.

Current Eye ResearchVol. 51(2)
Gaziantep University (TR)
Openalex Percentile: Top 17%
Air Quality and Health Impacts
1.20
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