Transplacental transfer efficiency of environmental chemicals in association with gestational diabetes mellitus
We found high TTRs for multiple short half-life chemicals and more recently introduced short-chain PFAS. Importantly, GDM was associated with increased transplacental efficiency of several classes of environmental chemicals, particularly chemicals with shorter half-lives.
Authors
- Yap Seng Chong (ORCID: https://orcid.org/0000-0002-7232-8473)
- Damaskini Valvi (ORCID: https://orcid.org/0000-0003-4633-229X)
- Brian W. Whitcomb (ORCID: https://orcid.org/0000-0002-8646-5823)
- C. Chen (ORCID: https://orcid.org/0000-0001-5301-1609)
- Youssef Oulhote
- Jonathan Huang (ORCID: https://orcid.org/0000-0002-5901-8403)
- Kok Hian Tan (ORCID: https://orcid.org/0000-0003-1945-0266)
- Jordana Leader (ORCID: https://orcid.org/0009-0006-0309-9140)
- Jessica Robinson
- Sharon Ng (ORCID: https://orcid.org/0000-0002-1572-1332)
- James Chun Yip Chan
- Johan G. Eriksson
- Shiao-Yng Chan
Institutions
- Agency for Science, Technology and Research (SG)
- University of Hawaiʻi at Mānoa (US)
- National University of Singapore (SG)
- National Taiwan University (TW)
- University of Massachusetts Amherst (US)
- Department of Public Health (AS)
- Singapore Institute for Clinical Sciences (SG)
- KK Women's and Children's Hospital (SG)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Environment International
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1016/j.envint.2025.109865
- Citations
- 1
- Primary Topic
- Effects and risks of endocrine disrupting chemicals
- Type
- article
- Field-Weighted Citation Impact
- 1.20