Comparative Effects of 4% Articaine and 2% Lignocaine on Salivary Biomarkers of Pain and Stress in Surgical Extraction of Impacted Mandibular Third Molars: A Prospective Observational Study

Compared to 2% lignocaine, 4% articaine demonstrated superior modulation of pain and stress biomarkers, supporting its preferential use in impacted mandibular third molar extraction.

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Publication Details

Journal
Cureus
Published
2025-10-14
DOI
https://doi.org/10.7759/cureus.94575
Primary Topic
Dental Anxiety and Anesthesia Techniques
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparative Effects of 4% Articaine and 2% Lignocaine on Salivary Biomarkers of Pain and Stress in Surgical Extraction of Impacted Mandibular Third Molars: A Prospective Observational Study

Mohd Younis Bhat, Reshma Hammannavar, Shahid Farooq, Nitika Mittal et al.
Cureus
Dental Anxiety and Anesthesia Techniques
article

Comparative Effects of 4% Articaine and 2% Lignocaine on Salivary Biomarkers of Pain and Stress in Surgical Extraction of Impacted Mandibular Third Molars: A Prospective Observational Study

Mohd Younis Bhat, Reshma Hammannavar, Shahid Farooq, Nitika Mittal, Neeta Padmawar, Nayan Gupta, Manish Sharma, Faisal Noor Ahmad
article en

Abstract

Compared to 2% lignocaine, 4% articaine demonstrated superior modulation of pain and stress biomarkers, supporting its preferential use in impacted mandibular third molar extraction.

CureusVol. 17(10)
Sarojini Naidu Medical College (IN), Pravara Institute of Medical Sciences (IN), Kothiwal Dental College and Research Centre (IN), Government Medical College (IN), Memorial Foundation (US), Government Dental College and Hospital (IN), Sharda University (IN)
Openalex Percentile: Top 59%
Dental Anxiety and Anesthesia Techniques
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