MoSe ₂ Nanoflower-Based Electrodes for High-Sensitivity and Rapid Detection of Ornidazole in Biomedical Diagnostics

Ornidazole (ORN) is a type of antibiotic that is largely consumed to treat various bacterial infections. Having said that, the overconsumption of ORN can lead to seizures and peripheral neuropathy. So, it is vital to periodically monitor the levels of ORN to safeguard human health. Therefore, we have fabricated 3D nanoflower-like structures of molybdenum diselenide (MoSe<sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub>) for high-performance electrochemical sensing of ORN. Prepared MoSe<sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> is subjected to morphological, topographical, and structural analysis through various spectroscopic techniques. MoSe<sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> nanoflower-modified electrodes showed a superior electrochemical surface area of 0.08 cm<sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> and enhanced conductivity (70 Ω). Further upon the electrochemical investigations, our MoSe₂-modified electrode displayed a good detection limit of 0.001 μM with a sensitivity of 0.36 μA μM<sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">–1</sup> cm<sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">–2</sup>. The repeatability and stability of the MoSe<sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> modified electrode are also evaluated. Finally, the fabricated electrode is probed for real sample analysis, which resulted in a high recovery of ORN. MoSe<sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> nanoflower-based electrochemical sensing of ORN proves to be an efficient platform for antibiotic sensing.