Trends in Mortality-Related to Peripheral Artery Disease and Chronic Obstructive Pulmonary Disease Comorbidity in the United States (1999–2023)
Although overall mortality related to PAD and COPD declined from 1999 to 2023, recent increases-particularly among older adults, males, the rural population, and specific geographic regions-highlight persistent disparities. While mortality from PAD or COPD alone has continued to decline, recent years have shown a reversal in patients with coexisting PAD and COPD, where mortality is rising disproportionately compared with either disease in isolation. These findings underscore the importance of continued surveillance and targeted chronic disease interventions to reduce mortality in high-risk populations.
Authors
- Sabit Saad Shafiq (ORCID: https://orcid.org/0009-0005-3211-2044)
- Iftikhar Khan (ORCID: https://orcid.org/0009-0004-9579-011X)
- Rida Noor
- Waleed Tariq (ORCID: https://orcid.org/0000-0001-8480-2710)
- Muhammad Ahmad Nadeem (ORCID: https://orcid.org/0009-0007-7201-2886)
- Zoya Aamir
- Muhammad F Shaikh
- Abu Baker Sheikh (ORCID: https://orcid.org/0000-0003-0503-6961)
- Zainab Malik (ORCID: https://orcid.org/0000-0002-1739-5606)
- Danyal Khan (ORCID: https://orcid.org/0000-0003-1892-5805)
- Bushra Ubaid
- Matia Fawad Memon
- Raheel Ahmed
- Neha Waseem
- Aleena Ihtasham
- Zainab Nouman
- Hafiz Muhammad Haris
Institutions
- Shaheed Benazir Bhutto Women University Peshawar (PK)
- Cleveland Clinic (US)
- King Edward Medical University (PK)
- University of New Mexico (US)
- CMH Lahore Medical College and Institute of Dentistry (PK)
- Bolan University of Medical and Health Sciences (PK)
- Jinnah Sindh Medical University (PK)
- Dow University of Health Sciences (PK)
- Imperial College London (GB)
Publication Details
- Journal
- Annals of Vascular Surgery
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1016/j.avsg.2025.09.049
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00