Cold Radiofrequency Ablation for Vertebral Bone Tumors: OsteoCool, Case Report and Literature Review

Background: The spine is the most frequently affected site in skeletal metastases, representing up to 70% of cases. These lesions can cause severe pain, fractures, and neurological deficits, significantly affecting quality of life. Conventional management includes opioids, bisphosphonates, surgery, and radiotherapy; however, these may be limited by delayed recovery, toxicity, or long-term side effects. Case presentation: We describe the case of a 38-year-old male with a vertebral lesion at T6, suggestive of metastasis, who underwent percutaneous cold radiofrequency ablation using the OsteoCool system combined with kyphoplasty. The procedure was completed without complications, achieving immediate pain relief and early mobilization, allowing hospital discharge within 24 hours. Discussion: Cold radiofrequency ablation offers a safe, minimally invasive alternative for the treatment of vertebral bone tumors, providing rapid pain control, reduced opioid use, and early initiation of adjuvant therapies. Conclusion: In selected patients, OsteoCool radiofrequency ablation can improve prognosis and quality of life, representing an effective option in both palliative and curative settings.