SARS-CoV-2 vaccination and plasma levels of psychotropic agents: a prospective cohort study
SARS-CoV-2 vaccination was not associated with essential alterations of psychotropic drug levels. Observed CRP increases did not reach concentrations that may be associated with elevated drug levels. Nevertheless, monitoring of CRP and drug levels is recommended to capture post-vaccine plasma level changes, particularly in patients receiving clozapine.
Authors
- Enza Messina (ORCID: https://orcid.org/0000-0002-4062-0824)
- Michael Paulzen (ORCID: https://orcid.org/0000-0003-4198-5160)
- Andreas Conca (ORCID: https://orcid.org/0000-0003-4841-7510)
- Georgios Schoretsanitis (ORCID: https://orcid.org/0000-0002-3851-4117)
- Agnese Raponi
- Nazar Kuzo (ORCID: https://orcid.org/0000-0003-2699-8422)
- Giancarlo Giupponi (ORCID: https://orcid.org/0000-0001-6430-0000)
Institutions
- Northwell Health (US)
- Hofstra University (US)
- Johannes Gutenberg University Mainz (DE)
- University of Zurich (CH)
- Centre for Mental Health (GB)
- Ospedale di Bolzano (IT)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Jülich Aachen Research Alliance (DE)
Publication Details
- Journal
- Expert Opinion on Drug Metabolism & Toxicology
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1080/17425255.2025.2575386
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00