Investigation on the relationship between renal NONO expression, fibrosis and prognosis in diabetic nephropathy
NONO expression levels correlate positively with MMP-9, collagen and renal damage indicators in renal tissues of DN patients. High NONO expression is linked to poor renal prognosis in DN. NONO may contribute to renal tissue fibrosis in DN by regulating MMP-9 levels.
Authors
- Hsien‐Tzung Liao (ORCID: https://orcid.org/0000-0001-5930-4840)
- Xingli Xu (ORCID: https://orcid.org/0000-0002-7188-5614)
- Shuang Yang (ORCID: https://orcid.org/0000-0002-4779-8553)
- Hanlu Ding
Institutions
- University of Electronic Science and Technology of China (CN)
- Chengdu Medical College (CN)
- Sichuan University (CN)
- First Affiliated Hospital of Chengdu Medical College (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-10-14
- DOI
- https://doi.org/10.3389/fendo.2025.1652391
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Postdoctoral Science Foundation