Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models
In conclusion, penfluridol exhibited cytotoxic effects in multiple preclinical PCa models. Further research is warranted to address the translational value of our findings.
Authors
- Gabri van der Pluijm (ORCID: https://orcid.org/0000-0002-1351-1884)
- Niven Mehra (ORCID: https://orcid.org/0000-0002-4794-1831)
- Tilly Aalders
- Maaike H. van der Mark (ORCID: https://orcid.org/0000-0002-2061-0020)
- J. Schalken
- Martin Puhr (ORCID: https://orcid.org/0000-0002-3858-9653)
- Geertje van der Horst (ORCID: https://orcid.org/0000-0003-1696-160X)
- Arjanneke F. van de Merbel
Institutions
- Innsbruck Medical University (AT)
- Radboud University Nijmegen (NL)
- Leiden University Medical Center (NL)
- Radboud University Medical Center (NL)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-10-14
- DOI
- https://doi.org/10.3389/fonc.2025.1685758
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00