Late‐Ulcerating Infantile Hemangioma Responsive to Propranolol: A Case and Literature Review

Ulceration is the most common complication of infantile hemangiomas (IHs) and typically occurs during the early proliferative phase in the first few months of life. We present a case of a 13-month-old female with a previously stable mixed-type IH on the left abdomen that developed a painful ulceration at 12 months. The ulceration responded rapidly to oral propranolol and resolved completely without recurrence. This case highlights late ulceration in IHs, supports the potential efficacy of propranolol beyond the proliferative phase, and is accompanied by a focused review of the literature on late-ulcerating presentations.

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Publication Details

Journal
Pediatric Dermatology
Published
2025-10-13
DOI
https://doi.org/10.1111/pde.70077
Primary Topic
Vascular Malformations and Hemangiomas
Type
article
Field-Weighted Citation Impact
0.00
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article

Late‐Ulcerating Infantile Hemangioma Responsive to Propranolol: A Case and Literature Review

Julia Gittler, Haley D. Heibel, M. Salman, R. Rookwood et al.
Pediatric Dermatology
Vascular Malformations and Hemangiomas
article

Late‐Ulcerating Infantile Hemangioma Responsive to Propranolol: A Case and Literature Review

Julia Gittler, Haley D. Heibel, M. Salman, R. Rookwood, N. Schiraldi
article en

Abstract

Ulceration is the most common complication of infantile hemangiomas (IHs) and typically occurs during the early proliferative phase in the first few months of life. We present a case of a 13-month-old female with a previously stable mixed-type IH on the left abdomen that developed a painful ulceration at 12 months. The ulceration responded rapidly to oral propranolol and resolved completely without recurrence. This case highlights late ulceration in IHs, supports the potential efficacy of propranolol beyond the proliferative phase, and is accompanied by a focused review of the literature on late-ulcerating presentations.

Pediatric Dermatology
Albert Einstein College of Medicine (US), Montefiore Medical Center (US), SUNY Downstate Health Sciences University (US), University of Toledo (US)
Openalex Percentile: Top 54%
Vascular Malformations and Hemangiomas
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Late‐Ulcerating Infantile Hemangioma Responsive to Propranolol: A Case and Literature Review — Julia Gittler, Haley D. Heibel, et al. · Pediatric Dermatology (2025) | TGRS Research Map | TGRS