Stable-isotope tracing reveals the role of corticosteroid receptors in driving cortisol-mediated central and peripheral glucose regulation in zebrafish
Overall, our results underscore the roles of GR and MR activation in elevating circulating energy substrates and facilitating tissue-level oxidative capacity and biomolecule synthesis from glucose metabolism in response to chronic cortisol stimulation in fish.
Authors
- Femilarani Antomagesh
- Mathilakath M. Vijayan (ORCID: https://orcid.org/0000-0002-4300-1965)
Institutions
- University of Calgary (CA)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-10-14
- DOI
- https://doi.org/10.3389/fendo.2025.1670637
- Primary Topic
- Zebrafish Biomedical Research Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Canterbury Medical Research Foundation
- Natural Sciences and Engineering Research Council of Canada